Vitro Toxicology
We are proud leaders in custom in vitro assay development, offering regulatory-aligned solutions for product safety and efficacy.
🧬 In Vitro Toxicology
Where Models Meet Precision
We are proud leaders in custom in vitro assay development, offering regulatory-aligned solutions for product safety and efficacy. Whether it’s cosmetic irritation, drug-induced hepatotoxicity, or skin sensitization, we design and validate models based on OECD TGs, ISO 10993, FDA Redbook, and ICH guidelines.
OECD In Vitro Toxicology Guidelines Offered:
- OECD TG 431 – In Vitro Skin Corrosion: Human Skin Model Test
- OECD TG 439 – In Vitro Skin Irritation: Reconstructed Human Epidermis Test
- OECD TG 492 – Reconstructed Human Cornea-like Epithelium Test Method (Eye Irritation)
- OECD TG 437 – Bovine Corneal Opacity and Permeability Test (BCOP)
- OECD TG 438 – Isolated Chicken Eye Test
- OECD TG 432 – 3T3 NRU Phototoxicity Test
- OECD TG 442A/B/C/D/E – Skin Sensitization (DPRA, KeratinoSens™, h-CLAT, U-SENS™)
- OECD TG 428 – Skin Absorption: In Vitro Method
Applications include:
- 3D reconstructed tissues (epidermis, airway, cornea, GI tract)
- Barrier integrity & permeation assays
- High-throughput cytotoxicity & apoptosis assays
- Neurotoxicity, hepatotoxicity, nephrotoxicity models
- iPSC-derived human cardiomyocytes
- Blood–brain barrier & inhalation models
- ISO 10993 biocompatibility suite (cytotoxicity, irritation, sensitization)