Genotoxicology

🔬 Genotoxicology

In Vitro Excellence for Global Dossiers

Awesomedge is a leading provider of in vitro genotoxicity studies, compliant with OECD TGs, ICH S2(R1), FDA Redbook, REACH, and more.
In Vitro Genotoxicology Test Battery:

• Ames Test (Bacterial Reverse Mutation Test) – OECD TG 471
• Salmonella typhimurium and E. coli strains ± S9
• In Vitro Mammalian Chromosome Aberration Test – OECD TG 473
• Human lymphocytes or CHO cells
• In Vitro Mammalian Cell Gene Mutation Test (HPRT/XPRT) – OECD TG 476
• In Vitro Micronucleus Test – OECD TG 487
• For clastogenic and aneugenic potential
• Mouse Lymphoma Assay (MLA/TK Assay) – OECD TG 490
• 6. Comet Assay (Single Cell Gel Electrophoresis) – For DNA strand breaks (Emerging, based on validation protocols)

We ensure results are regulatory-ready for FDA, EMA, PMDA, and CIBRC filings.