Safety Pharmacology

⚠️ Safety Pharmacology

hERG and Beyond

We provide specialized in vitro safety pharmacology testing, including cardiac, neurological, and respiratory endpoints.

Key Assays:

• hERG Assay (Human Ether-à-go-go Related Gene)
• Patch-clamp or fluorescence-based
• ICH S7B and FDA-compliant
• Detects QT interval prolongation risk
• Suitable for IND/NDA regulatory filings
• iPSC-derived cardiomyocyte-based cardiac assays
• Neurotoxicity screening (calcium imaging, MEA systems)
• Respiratory and CNS functional assays (as per ICH S7A)

All safety pharmacology assays are conducted in accordance with GLP, ICH, and FDA guidelines.